Therapeutic areas

PROOF OF CONCEPT TRIALS

proof of concept trials

ARENSIA delivers high degree of scientific and logistical expertise for Phase I/Ib/IIa and PROOF OF CONCEPT patient studies.

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COVID-19 RESEARCH

COVID-19 RESEARCH

ARENSIA has contributed to numerous research projects with innovative compounds enrolling more than 1,500 COVID-19 patients.

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REGULATORY PROCESS

regulatory process

ARENSIA has the know-how to successfully manage the regulatory process in various Eastern European countries.

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THERAPEUTIC AREAS

ARENSIA contributes with outstanding recruitment rates to early phase projects in the following therapeutic areas: ONCOLOGY, IMMUNO-INFLAMMATORY, CARDIOVASCULAR, DIABETES/METABOLIC, RESPIRATORY, HEPATOLOGY, NEPHROLOGY, GASTROENTEROLOGY, INFECTIOUS DISEASES HCV/HBV/HIV, UROLOGY, DERMATOLOGY, NEUROLOGY, PSYCHIATRY, OPHTHALMOLOGY, HEMATOLOGY.

We are enabling patients the access to the most innovative medicines early on in the drug development process and offer Sponsors the opportunity to reduce the recruitment periods for their programs and progress faster to later phases of research.

Disease diagnostics at ARENSIA locations follows US and European guidelines. Patient files are extraordinarily well documented, which helps for accurate patient selection. Especially in immunology and oncology, the patient pools are mainly naive of expensive biological, respectively immuno-therapies. In other indications (e.g. cardiovascular, metabolic, respiratory, neurosciences) patients are generally treated with therapies approved recently in Western countries, while a large pool of patients are still being treated naive (e.g. treatment naive T2D patients, or T2D patients on metformin monotherapy).

Below are examples of patient populations within key therapeutic areas at ARENSIA:

IMMUNO-INFLAMMATORY View information

  • Rheumatoid Arthritis
  • Inflammatory Arthritis
  • Osteoarthritis
  • Psoriasis
  • Psoriatic Arthritis
  • Atopic Dermatitis
  • Ankylosing Spondylitis
  • Lupus (all forms)
  • Ulcerative Colitis
  • Inflammatory Bowel Disease
  • Crohn's Disease
  • Asthma
  • Other

ONCOLOGY View information

  • Colorectal cancer
  • Breast cancer
  • Lung cancer
  • Skin cancer
  • Hemoblastosis
  • Gastric cancer
  • Cervical cancer
  • Prostate cancer
  • Liver cancer
  • Thyroid cancer
  • Hematology-Oncology
  • Other cancers

CARDIOVASCULAR View information

  • Arterial Hypertension
  • Pulmonary Hypertension
  • Chronic Heart Failure (NYHA II-IV)
  • Coronary Heart disease: Stable Angina
  • Acute Coronary Syndrome, MI
  • Arrhythmia
  • Hypertrophic Cardiomyopathy
  • Valvular diseases
  • Peripheral Artery diseases
  • Metabolic Syndrome

RENAL & HEPATIC FAILURE View information

  • Renal Impairment: Mild, Moderate, Severe
  • ESRD (with & without dialysis)
  • Hepatic Impairment: Child Pugh A, B

INFECTIOUS DISEASES View information

  • COVID-19 (mild, moderate, severe / contacts / post-COVID syndrome)
  • Hepatitis C (GT1b, GT3, GT2, GT4)
  • Hepatitis B
  • HIV
  • Co-infections
  • Other infectious diseases

METABOLICS View information

  • Type 1/ Type 2 Diabetes
  • Diabetic Nephropathy
  • Diabetic Neuropathy
  • Diabetic Retinopathy
  • Impaired Glucose Tolerance
  • Dyslipidemia
  • Obesity

RESPIRATORY View information

  • Asthma
  • COPD
  • Interstitial lung diseases Sarcoidosis
  • Acute respiratory infections

NEUROSCIENCES View information

  • Depression, OCD
  • Generalized Anxiety, Panic
  • Post Traumatic Stress
  • Dementias (Alzheimer's, vascular)
  • Epilepsies
  • Psychosomatic disorders
  • Multiple Sclerosis
  • Neurodegenerative diseases (e.g. ALS)
  • Parkinson's disease
  • Pain (neuropathic, chronic, acute)
  • Sleep disorders
  • Meniere's disease
  • Peripheral neuropathies
  • Cranial nerve diseases
  • Nerve and muscle disorders
  • Chronic fatigue syndrome
  • Other rare/special populations

OPHTHALMOLOGY

  • Glaucoma
  • Cataract
  • Conjunctivitis
  • Dry eye
  • Macular Degeneration
  • Macular Edema

HEMATOLOGY

  • Idiopathic Thrombocytopenic Purpura (ITP)
  • Hemophilia
  • Hematology-Oncology

GYNAECOLOGY / UROLOGY

  • Abnormal Uterine Bleeding
  • Endometriosis
  • Fibroids
  • Menopause
  • Bladder Infection (UTI)
  • Bladder Control (UI)
  • Urinary Tract Infection (UTI)

DERMATOLOGY

  • Acne
  • Psoriasis
  • Atopic Dermatitis
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